|
Egg donation is used in many situations. The most common
are:
- Menopause: Natural, whether on time, in the 50s or Premature,before 40s.It may happen spontaneously or subsequent to surgery such as removal of Large portions of the ovaries or of the uterus(removal of the conduit of the blood flow).
- Destruction of the ovaries: can occur as a result of viral infections,orchitis, but it may follow chemotherapy or radiation treatment with or whithout return of the ovarian function once the treatment is concluded.
- Presence of the ovaries but poor Ovarian Stimulation with
repeatedly bad outcome and lately,the presence of a low level of the AMH(Anti Mullerian Hormone,one of the predictors of the ovarian reserve).
- Fluctuating high levels of FSH(Follicular Stimulating Hormone) and of Estradiol on day 2 or 3 of the menstruation/menstrual cycle.
- Known carriers of genetic diseases present on both or dominant in one of the members of the couple(they
may want to perform an IVF cycle and test the embryos
by PGD).
- Male gay couple in need of a donated egg to be fertilized with one of the couple'sperm.
- Failure to produce eggs or enough eggs during Ovarian
Stimulation for either Insemination or In Vitro Fertilization.
- Poor quality eggs,embryos, abnormal embryos as demonstrated by PGD(Preimplantation Genetic Diagnosis)
or by a poor outcome in several IVF cycles.
For all these reasons we interview many young fertile
volunteers, screen them extensively for infectious diseases, genetic
and psychological evaluation, ultrasound, physical and hormonal examinations and we match the couple with the desired donor. Sometomes we advertise for the couple or we direct them to an agency that specialises in finding Donor Eggs. However most of the time we're able to
quickly match the couple with one of our donors.
Once the donors are accepted we screen the couple as well
the way we screened the donors.
Therafter, we synchronize the cycle of the donor with the one of the recipient: in the recipient we try to achieve an optimal width if the endometrial stripe, similar to what
naturally happens in a conceptual cycle. This growth is achieved by using Estrogen in a gradual fashion (no injections needed!). During this time the donor goes through controled ovarian hyperstimulation with injected medication, usually a combination stimlating drugs combined with medication that keeps the brain's natural stimulating hormines (FSH-Follicular Stimulating Hormone and LH-Luteinizing Hormone) on "Neutral" or by supressing brain's above hormones while we directly stimulate the ovaries with our medication. The idea is to keep the ovaries from getting Hyperstimulated from two sources: internal, from her own brain, and external from medication we administer!
When the donor is close to egg retrieval we start the recipent on progesterone in addition to estrogen she continues to get.The donor, if ready, is getting the last injection HCG (Human Menopausal Gonadotropin) which will
mature the eggs and detach them from the conection ti the environment and they'll be free floating inside their shell: the follicles, which in fact we monitor by measuring their growth,not the growth of the eggs which are invisible to the naked eye. Now the follicles will be punctured wirhin 36 hours and the eggs will be aspirated through the vagina with the help of the transvaginal probe to which a needle is attached.
after a little rest the ogg will be fertilized with the recipient husband sperm and in few days the recipient will be transfered to her uterus the donor eggs fertilized with her partner sperm either at the stage of 6 to 8 cells or
morula or even later (4 to 5 days of development in the incubator) blastocyst.
We have served many,many couples from US but we helped many couples from all over the world assisting them with all the necessary needed to make their fertility journey
a beautiful and a memorable event.
Please call us for detail at:
Tel. 212 721 4545
Fax.212 721 4598
Email. dovgoldsteinmd@hotmail.com |
|
